Monday, April 18, 2011

BIOLOGICS - PATENT EXPIRY

CompanyDrug Brand NameIndication Mech. Of ActionLAUNCH YEARPatent ExpiryWW Sales -2009( $m)
LLYHumulinDiabetes Insulin supplement1994Expired1,022
LLYHumatropeHormonal DisorderGrowth hormone 1987Expired449
LLYHumalogDiabetesFast acting rDNA insulin analouge199620131,959
LLYErbituxColorectal CancerMonoClonal Antibody20042014391
BMYOrenciaRheumatoid ArthritisInhibit co stimulation of T cells20052016602
SGPRemicadeRheumatoid ArthritisTNF alpha inhibitor199820142,140
SGPPEG-Intron + Intron AHCVErythropoietin200220201,151
PFEEnbrel (International only)Rheumatoid ArthritisTNF alpha inhibitor199920122,852
JNJRemicadeRheumatoid ArthritisTNF alpha inhibitor19982014998
JNJProcrit/Eprex (Epoetin Alfa)AnemiaErythropoietin199220132,214
ABTHumiraRheumatoid Arthritis TNF alpha inhibitor200320161,024
NOVNLucentisWET AGE AMDVEGF inhibitor200720191,232
NOVN XolairASTHAMA / COPDMonoClonal Antibody20052018338
SANApidradiabetesInsulin20042018137
ROGMabThera/RituxanNon hodgkins lymphomaBinds with CD20 and cause apoptosis of cell199720186,087
ROGHerceptinbreast cancerBinds with HER2/neu receptor199820195,266
ROGAvastincolorectal cancerVEGF inhibitor200420196,222
ROGLucentisWET AGE AMDVEGF-A  inhibitor200520191,198
ROG Xolairasthama / copdantibody20032018620
ROGPulmozymeCystic Fibrosis1993Expired501
ROGCopegus + PegasysHBVInterferon /Nucleoside inhibitor200220181,655
ROGActemraRheumatoid ArthritisIL-6 recptor inhibitor2010202293
ROGNeoRecormon/EpoginAnemiaErythropoietinExpired1,560
NOVOHuman InsulinDiabetesInsulinExpired11,315
NOVONovoRapidDiabetesInsulin200020149,749
NOVONovoMixDiabetesInsulin200020146,499
NOVONovoSevenHemphiliaActivated Factor VII199920117,072
NOVONorditropinGrowth Disordersgrowth hormone200020144,401
NOVOHormone Replacement TherapyHormonal DisorderHormone01,744
AZNSynagis/ NumaxFluMonoClonal AntibodyBio20201,261