Monday, January 30, 2012

CABG has Mortality benefits over PCI in high risk patients

Results from a large observational study (ASCERT), suggests that CABG is associated with long term mortality benefits when compared to PCI in the high risk patients (age>65, 2 or 3 vessel disease).  189,793 patients were observed for a period of 4 years; of which 103,549 received PCI and 86,244 underwent CABG.  The survival advantage associated with CABG progressively increased over the years.

At 4 years there was a 22% risk reduction in adjusted mortality in the CABG group compared to the PCI group (RR = 0.78, CI 0.74-0.82). A similar pattern was observed in patients regardless of age, gender, diabetes status, and ejection fraction.

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